| Monarch Ortholog Phenotypes
|
Human (35 sources):
Anteverted nares,
Axial hypotonia,
Brisk reflexes,
Cerebellar hypoplasia,
Cryptorchidism,
Delayed myelination,
Diabetes mellitus,
Elevated circulating hepatic transaminase concentration,
External genital hypoplasia,
Feeding difficulties,
Full cheeks,
Generalized myoclonic seizure,
Gingival overgrowth,
Global developmental delay,
High palate,
Hypogonadism,
Hypoplasia of the corpus callosum,
Hypotonia,
Hypsarrhythmia,
Intellectual disability,
Intellectual disability, profound,
Jaundice,
Microcephaly,
Moderate albuminuria,
Narrow forehead,
Neonatal hypotonia,
Optic atrophy,
Osteopenia,
Pathologic fracture,
Ptosis,
Recurrent respiratory infections,
Seizure,
Simplified gyral pattern,
Small scrotum,
Tented upper lip vermilion
[+]
|
|
Mouse (3 sources):
abnormal vocalization,
embryonic lethality prior to organogenesis,
preweaning lethality, complete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.