tmem70 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (114)

Interactants (225)

XB-GENEPAGE-989399

Gene Symbol: tmem70 Gene Name: transmembrane protein 70

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal axis elongation (1 source), abnormal gastrulation (1 source), abnormally delayed closure of blastopore (1 source), absent head (1 source), absent tail (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the head (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + tmem70 MO (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (54 sources): 3-Methylglutaconic aciduria, Abnormal aortic valve morphology, Abnormal pulmonary valve morphology, Abnormality of mitochondrial metabolism, Abnormality of the kidney, Anteverted nares, Aplasia/Hypoplasia of the corpus callosum, Arrhythmia, Ataxia, Camptodactyly of finger, Cataract, Cerebral cortical atrophy, Congestive heart failure, Cryptorchidism, Encephalopathy, Failure to thrive, Flat face, Flat occiput, Flexion contracture, Gastroparesis, Generalized hypotonia, Global developmental delay, Growth delay, Hepatomegaly, Hyperalaninemia, Hyperammonemia, Hypertension, Hypertrophic cardiomyopathy, Hypospadias, Hypotonia, Increased circulating lactate concentration, Infectious encephalitis, Intellectual disability, moderate, Intention tremor, Intrauterine growth retardation, Lactic acidosis, Leukoencephalopathy, Long philtrum, Low-set ears, Microcephaly, Microretrognathia, Moderate global developmental delay, Oligohydramnios, Premature birth, Psychomotor retardation, Respiratory insufficiency, Retrognathia, Seizure, Short philtrum, Small for gestational age, Tremor, Umbilical hernia, Wide mouth, Wide nasal bridge [+]
Mouse (23 sources): abnormal embryo size, abnormal embryo turning, abnormal enzyme/coenzyme level, abnormal mitochondrial crista morphology, abnormal mitochondrial physiology, abnormal oxidative phosphorylation, abnormal somite shape, cellular phenotype, decreased embryo size, decreased ventricle muscle contractility, delayed embryo turning, delayed heart development, delayed rostral neuropore closure, delayed somite formation, disorganized mitochondrial cristae, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality prior to tooth bud stage, growth/size/body region phenotype, homeostasis/metabolism phenotype, oxidative stress, preweaning lethality, complete penetrance, small heart [+]
View all ortholog results at Monarch