| Monarch Ortholog Phenotypes
|
Human (25 sources):
Abnormality of the cerebral white matter,
Cataract,
Cerebellar atrophy,
Cerebral cortical atrophy,
Clonus,
Decreased fetal movement,
Delayed myelination,
Generalized hypotonia,
Hyperreflexia,
Hypoplasia of the corpus callosum,
Macrotia,
Microcephaly,
Narrow palate,
Optic atrophy,
Plagiocephaly,
Profound global developmental delay,
Progressive flexion contractures,
Proptosis,
Protruding ear,
Scoliosis,
Seizure,
Skeletal muscle atrophy,
Sloping forehead,
Spastic tetraparesis,
Talipes equinovarus
[+]
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Mouse (7 sources):
abnormal circulating total protein level,
abnormal embryo development,
abnormal embryo size,
abnormal startle reflex,
decreased startle reflex,
embryonic lethality prior to tooth bud stage,
preweaning lethality, complete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.