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Summary Expression Phenotypes Gene Literature (58) GO Terms (6) Nucleotides (44) Proteins (28) Interactants (291) Wiki
XB-GENEPAGE-992304

th     tyrosine hydroxylase

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally peramorphic growth of hindlimb bud (4 sources), increased size of the hindlimb bud (4 sources), abnormal hindlimb bud (2 sources), increased thickness of the epidermis (2 sources), increased width of hindlimb bud (2 sources), abnormal iridophore (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: th assayed (9 sources)
Computed annotations: th assayed (3 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + thra TALEN (5 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (36 sources): Abnormality of extrapyramidal motor function, Ataxia, Babinski sign, Bradykinesia, Brisk reflexes, Central hypotonia, Constipation, Decreased CSF homovanillic acid, Delayed speech and language development, Excessive salivation, [+]
Mouse (30 sources): abnormal active avoidance behavior, abnormal adrenaline level, abnormal associative learning, abnormal conditioned taste aversion behavior, abnormal cued conditioning behavior, abnormal eye electrophysiology, abnormal fetal cardiomyocyte morphology, abnormal heart development, abnormal learning/memory/conditioning, abnormal noradrenaline level, [+]

View all ortholog results at Monarch