| Monarch Ortholog Phenotypes
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Human (3 sources):
Cleft palate,
Hypouricemia,
Nephrolithiasis
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Mouse (21 sources):
abnormal circulating lipid level,
abnormal enterocyte physiology,
abnormal feces composition,
abnormal heart echocardiography feature,
abnormal renal reabsorption,
decreased respiratory quotient,
decreased urine osmolality,
decreased urine pH,
dilated renal tubules,
increased basal metabolism,
increased body fat mass,
increased circulating creatinine level,
increased energy expenditure,
increased liver free fatty acids level,
increased liver triglyceride level,
increased oxygen consumption,
increased percent body fat/body weight,
increased urine sodium level,
no abnormal phenotype detected,
prenatal lethality, incomplete penetrance,
renal/urinary system phenotype
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.