| Monarch Ortholog Phenotypes
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Human (28 sources):
Abnormal localization of kidney,
Abnormal palate morphology,
Ankyloglossia,
Atrial septal defect,
Bifid uvula,
Brachydactyly,
Chorioretinal coloboma,
Cleft palate,
Coloboma,
Conductive hearing impairment,
Coronal hypospadias,
Cryptorchidism,
Dimple chin,
Epicanthus,
Flat face,
Hearing impairment,
Hypospadias,
Iris coloboma,
Macrotia,
Malar flattening,
Microcornea,
Protruding ear,
Radioulnar synostosis,
Sensorineural hearing impairment,
Short stature,
Short toe,
Toe syndactyly,
Ulnar deviation of finger
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Mouse (11 sources):
abnormal bone mineralization,
abnormal osteoblast differentiation,
abnormal palatal rugae morphology,
abnormal vomer bone morphology,
decreased body length,
decreased palatine bone horizontal plate size,
no abnormal phenotype detected,
palate bone hypoplasia,
perinatal lethality, incomplete penetrance,
persistent oronasal membrane,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.