hcrt Phenotypes

XB-GENEPAGE-996571

Gene Symbol: hcrt Gene Name: hypocretin (orexin) neuropeptide precursor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hcrt assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal circadian temperature homeostasis, abnormal locomotor activation, abnormal locomotor behavior, abnormal non-rapid eye movement sleep pattern, abnormal paradoxical sleep pattern, abnormal sleep pattern, abnormal systemic arterial blood pressure, behavioral arrest, decreased grip strength, decreased locomotor activity, decreased mean systemic arterial blood pressure, decreased vertical activity, fragmentation of sleep/wake states, increased frequency of paradoxical sleep, increased pulmonary respiratory rate, increased susceptibility to age related obesity, increased vertical activity [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal circadian temperature homeostasis, abnormal locomotor activation, abnormal locomotor behavior, abnormal non-rapid eye movement sleep pattern, abnormal paradoxical sleep pattern, abnormal sleep pattern, abnormal systemic arterial blood pressure, behavioral arrest, decreased grip strength, decreased locomotor activity, [+]