dock7 dedicator of cytokinesis 7
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
|abnormal development of embryo (1 source), abnormal head morphology (1 source), abnormal somite morphology (1 source), abnormal tail morphology (1 source), abnormal ventral trunk morphology (1 source), decreased length of anterior-posterior axis (1 source), tail abnormally curved dorsally (1 source)|
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
|Computed annotations: dock7 assayed (3 sources)|
These are short form descriptions of experiments using reagents targeting the gene of interest.
|Xtr Wt + dock7 MO (2 sources)|
|Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources):
Abnormality of the pinna,
Broad nasal tip,
Cerebral visual impairment,
Global developmental delay,
Hypoplasia of the corpus callosum,
Hypoplasia of the pons,
Low anterior hairline,
Narrow forehead, Periorbital fullness, Seizure, Short philtrum, Telecanthus, Thick eyebrow, Thick vermilion border[+]
Mouse (15 sources):
abnormal brown adipose tissue mass,
abnormal maternal behavior,
abnormal social investigation,
decreased body length,
decreased digit pigmentation,
decreased platelet ADP level,
decreased white adipose tissue amount,
diluted coat color,
hearing/vestibular/ear phenotype, homeostasis/metabolism phenotype, immune system phenotype, non-pigmented tail tip, vision/eye phenotype[+]
View all ortholog results at Monarch