abnormal spinal cord ventral horn morphology, abnormal stria vascularis morphology, abnormal strial intermediate cell morphology, behavior/neurological phenotype, cochlear outer hair cell degeneration, decreased cochlear outer hair cell number, decreased embryo size, decreased endocochlear potential, decreased erythrocyte cell number, decreased fetal weight, decreased hepatocyte proliferation, decreased skeletal muscle fiber size, decreased susceptibility to kidney reperfusion injury, decreased trophoblast giant cell number, dilated liver sinusoidal spaces, disorganized placental labyrinth, dissociated hepatocytes, ectopic melanocytes, ectopic skeletal muscle, hindlimb paralysis, hyperpigmentation, impaired liver regeneration, increased cutaneous melanoma incidence, increased hair follicle number, increased mammary adenocarcinoma incidence, increased mammary gland tumor incidence in breeding females, increased mammary gland tumor incidence in virgin females, increased melanoma incidence, increased metastatic potential, increased satellite cell number, increased skin tumor incidence, lethality throughout fetal growth and development, complete penetrance, liver hypoplasia, mammary gland duct hyperplasia, organ of Corti degeneration, premature death, premature hair follicle generation, small liver, spiral ligament degeneration, thick skin, thin stria vascularis