Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (0) GO Terms (69) Nucleotides (281) Proteins (54) Interactants (77) Wiki
XB-GENEPAGE- 967774

Gene Ontology
Category GO Terms Show all Annotations
Molecular Function
    [+]
  1. 3'-5' DNA helicase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  2. [+]
  3. 3'-5' DNA/RNA helicase activity
    Annotations:
    1. F6V9Y0 (TrEMBL, spp.: X.tropicalis)
    2. A0A8J0SM75 (TrEMBL, spp.: X.tropicalis)
    3. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  4. [+]
  5. 3'-5' RNA helicase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  6. [+]
  7. ATP binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  8. [+]
  9. ATP hydrolysis activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  10. [+]
  11. DNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  12. [+]
  13. DNA helicase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  14. [+]
  15. DNA replication origin binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  16. [+]
  17. RISC complex binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  18. [+]
  19. RNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  20. [+]
  21. RNA helicase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  22. [+]
  23. RNA polymerase II cis-regulatory region sequence-specific DNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  24. [+]
  25. RNA polymerase binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  26. [+]
  27. RNA stem-loop binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  28. [+]
  29. chromatin DNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  30. [+]
  31. double-stranded DNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  32. [+]
  33. double-stranded RNA binding
    Annotations:
    1. F6V9Y0 (TrEMBL, spp.: X.tropicalis)
    2. A0A8J0SM75 (TrEMBL, spp.: X.tropicalis)
    3. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  34. [+]
  35. hydrolase activity
    Annotations:
    1. F6V9Y0 (TrEMBL, spp.: X.tropicalis)

  36. [+]
  37. importin-alpha family protein binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  38. [+]
  39. mRNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  40. [+]
  41. metal ion binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  42. [+]
  43. nucleoside triphosphate diphosphatase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  44. [+]
  45. polysome binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  46. [+]
  47. promoter-specific chromatin binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  48. [+]
  49. ribonucleoside triphosphate phosphatase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  50. [+]
  51. sequence-specific mRNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  52. [+]
  53. single-stranded 3'-5' DNA helicase activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  54. [+]
  55. single-stranded DNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  56. [+]
  57. single-stranded RNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  58. [+]
  59. transcription coactivator activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  60. [+]
  61. triplex DNA binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)


Biological Process
    [+]
  1. DNA duplex unwinding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  2. [+]
  3. DNA replication
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  4. [+]
  5. DNA-templated transcription termination
    Annotations:
    1. F6V9Y0 (TrEMBL, spp.: X.tropicalis)
    2. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  6. [+]
  7. G-quadruplex DNA unwinding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  8. [+]
  9. RISC complex assembly
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  10. [+]
  11. RNA secondary structure unwinding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  12. [+]
  13. alternative mRNA splicing, via spliceosome
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  14. [+]
  15. cellular response to tumor necrosis factor
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  16. [+]
  17. global gene silencing by mRNA cleavage
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  18. [+]
  19. mRNA transport
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  20. [+]
  21. positive regulation of DNA repair
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  22. [+]
  23. positive regulation of DNA replication
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  24. [+]
  25. positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  26. [+]
  27. positive regulation of NF-kappaB transcription factor activity
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  28. [+]
  29. positive regulation of RNA export from nucleus
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  30. [+]
  31. positive regulation of cytoplasmic translation
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  32. [+]
  33. positive regulation of fibroblast proliferation
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  34. [+]
  35. positive regulation of miRNA-mediated gene silencing
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  36. [+]
  37. positive regulation of polysome binding
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  38. [+]
  39. positive regulation of transcription by RNA polymerase II
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  40. [+]
  41. regulation of cytoplasmic translation
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)

  42. [+]
  43. regulation of mRNA processing
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)


Cellular Component
    [+]
  1. CRD-mediated mRNA stability complex
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  2. [+]
  3. RISC complex
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  4. [+]
  5. RISC-loading complex
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  6. [+]
  7. actin cytoskeleton
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  8. [+]
  9. cytoplasm
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  10. [+]
  11. cytoplasmic ribonucleoprotein granule
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  12. [+]
  13. microtubule organizing center
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  14. [+]
  15. nuclear body
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  16. [+]
  17. nuclear stress granule
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  18. [+]
  19. nucleolus
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  20. [+]
  21. nucleoplasm
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  22. [+]
  23. nucleus
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  24. [+]
  25. obsolete polysomal ribosome
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  26. [+]
  27. obsolete polysome
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  28. [+]
  29. perichromatin fibrils
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)
  30. [+]
  31. ribonucleoprotein complex
    Annotations:
    1. Q68FK8 (Swiss-Prot, spp.: X.laevis.L)