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Summary Expression Phenotypes Gene Literature (5) GO Terms (14) Nucleotides (273) Proteins (59) Interactants (136) Wiki
XB-GENEPAGE-1016045
???displayGene.symbol???:
 pycr1

???displayGene.name???: 
pyrroline-5-carboxylate reductase family, member 1

???displayGene.synonyms???
arcl2b , p5c , p5cr , pig45 , pp222 , pro3 [+] ( Nomenclature history )

???displayGene.geneFunction???
Pyrroline-5-carboxylate reductase

AI Protein Function :
The gene pycr1 encodes an enzyme involved in proline biosynthesis, converting glutamate to pyrroline-5-carboxylate and subsequently to proline while utilizing NAD(P)H as a cofactor; it localizes to the...[+]


InterPro :
P5CR dimer, P5C Rdtase cat N, NAD(P)-bd dom sf, 6-PGluconate DH-like C sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
cutis laxa [+]

MIM:
CUTIS LAXA, AUTOSOMAL RECESSIVE, TYPE IIB; ARCL2B [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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