The tfdp1 gene encodes a transcription factor that heterodimerizes with e2f proteins to regulate cell cycle progression by binding to specific DNA promoter sequences. In early development, it is expres...[+]

The tfdp1 gene encodes a transcription factor that heterodimerizes with e2f proteins to regulate cell cycle progression by binding to specific DNA promoter sequences. In early development, it is expressed in the neural plate, brain, eye, branchial arches, and pronephros. The protein localizes to the nucleus where it functions as part of the dnabinding transcription factor complex involved in controlling the g1/s transition of the cell cycle. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD