The wdr26 gene encodes a WD repeat-containing protein that functions in protein-protein interactions and signal transduction. In Xenopus laevis and Xenopus tropicalis, wdr26 is involved in embryonic de...[+]

The wdr26 gene encodes a WD repeat-containing protein that functions in protein-protein interactions and signal transduction. In Xenopus laevis and Xenopus tropicalis, wdr26 is involved in embryonic development, including neural tube formation and mesoderm patterning. The protein localizes to the cytoplasm and nucleus, where it participates in cilia function and cell cycle regulation. It interacts with components of signaling pathways, such as Wnt and Hedgehog, influencing cell proliferation and differentiation. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD