The avpi1 gene encodes a vasotocin-neurophysin vt precursor protein which is cleaved into neurohypophysial hormones arginine vasotocin and neurophysin-vt. This neuropeptide hormone functions in water b...[+]

The avpi1 gene encodes a vasotocin-neurophysin vt precursor protein which is cleaved into neurohypophysial hormones arginine vasotocin and neurophysin-vt. This neuropeptide hormone functions in water balance, vascular regulation, and reproductive behaviors through its action as a g-protein coupled receptor ligand. Expression is localized to the hypothalamus, pituitary gland, and preoptic area with protein secretion into the bloodstream from the neurohypophysis. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD