The ube2r2 gene in Xenopus laevis and Xenopus tropicalis encodes a ubiquitin-conjugating enzyme that functions in the ubiquitin-proteasome pathway, facilitating protein ubiquitination for targeted degr...[+]

The ube2r2 gene in Xenopus laevis and Xenopus tropicalis encodes a ubiquitin-conjugating enzyme that functions in the ubiquitin-proteasome pathway, facilitating protein ubiquitination for targeted degradation. It is involved in cell cycle regulation, DNA damage response, and apoptosis, playing roles in embryonic development and cell cycle progression. The protein is involved in DNA repair processes and is essential for proper cell cycle progression during early development. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD