The gja4 gene encodes connexin 37, a gap junction protein forming intercellular channels for direct electrical and chemical communication between adjacent cells. In oocytes, its expression supports mat...[+]

The gja4 gene encodes connexin 37, a gap junction protein forming intercellular channels for direct electrical and chemical communication between adjacent cells. In oocytes, its expression supports maturation. During early development, it contributes to cell-to-cell communication among blastomeres, facilitating proper embryonic development. The protein is localized to the plasma membrane. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD