The dscam protein functions as an immunoglobulin superfamily cell adhesion molecule and axon guidance receptor involved in neural development, mediating self-avoidance in retinal axons which prevents f...[+]

The dscam protein functions as an immunoglobulin superfamily cell adhesion molecule and axon guidance receptor involved in neural development, mediating self-avoidance in retinal axons which prevents fasciculation of sister axons from the same ganglion cell to ensure complete coverage of the optic tectum; it is a transmembrane protein localized to the cell membrane. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD