The ube2z gene encodes a ubiquitin-conjugating enzyme that functions in the ubiquitin-proteasome pathway, facilitating the transfer of ubiquitin to substrate proteins for degradation. In Xenopus laevis...[+]

The ube2z gene encodes a ubiquitin-conjugating enzyme that functions in the ubiquitin-proteasome pathway, facilitating the transfer of ubiquitin to substrate proteins for degradation. In Xenopus laevis and Xenopus tropicalis, the ube2z protein localizes to the cytoplasm and nucleus, where it participates in protein ubiquitination processes, including roles in cell cycle regulation and protein turnover. The protein acts as an E2 ubiquitin-conjugating enzyme, involved in the ubiquitin-proteasome system for targeted protein degradation. [-]

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