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Summary Expression Gene Literature (8) GO Terms (11) Nucleotides (299) Proteins (57) Interactants (389) Wiki
Gene Symbol:

Gene Name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

( Add synonyms , Nomenclature history )

Gene Function:
Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase

Protein Function :
Synthesis and degradation of fructose 2,6-bisphosphate.

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External Links:
Xenbase Gene ID XB-GENE-1001570 XB-GENE-17337999 XB-GENE-6256300
Gene Symbol pfkfb4 pfkfb4.L pfkfb4.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 407880
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pfkfb4 pfkfb4.L pfkfb4.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards PFKFB4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Pfkfb4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Pfkfb4 Ensembl
ZFIN, AGR ZFIN, AGR pfkfb4b pfkfb4a ZFIN Ensembl
fruit fly
First Pfkfb (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) isoforms display a tissue-specific and dynamic expression during Xenopus laevis development., Gene Expr Patterns 2013                                                          
Most Recent The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation., Development 2020                                      
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 5 terms 5 terms
PANTHER pfkfb4
KEGG Pathways K19030 K19030
KOG [G] Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pfkfb4
Morpholinos pfkfb4 MO2 pfkfb4 MO2 pfkfb4 MO1 , pfkfb4 MO2
ORFs pfkfb4 ORF1 pfkfb4.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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