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Summary Expression Phenotypes Gene Literature (1) GO Terms (1) Nucleotides (107) Proteins (60) Interactants (382) Wiki
XB-GENEPAGE-1002068
???displayGene.symbol???:
 hmgcl

???displayGene.name???: 
3-hydroxy-3-methylglutaryl-CoA lyase

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( Nomenclature history )

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Hydroxymethylglutaryl-CoA lyase

Protein Function :
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Te...[+]


InterPro :
YchF C, P-loop NTPase, GTP binding domain, Beta-grasp dom sf, [+]

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Diseases: 


External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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