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Summary Expression Gene Literature (325) GO Terms (45) Nucleotides (188) Proteins (31) Interactants (1174) Wiki
Gene Symbol:

Gene Name:
dishevelled segment polarity protein 2

Xdsh , dsh , dishevelled , dvl , Xdsh2 ( Add synonyms , Nomenclature history )

Gene Function:
wnt signal transduction

Protein Function :
Involved in at least 2 independent signaling cascades, controlling cell fate via canonical Wnt signaling and cell polarity via a planar cell polarity (PCP) cascade. Acts synergistically with dal/dapple...[+]

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External Links:
Xenbase Gene ID XB-GENE-1017461 XB-GENE-1017467 XB-GENE-17345953
Gene Symbol dvl2 dvl2.L dvl2.S
Chromosome Chr3 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 780117
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dvl2 dvl2.L dvl2.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards DVL2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Dvl2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
Dvl2 Ensembl
ZFIN, AGR dvl2 ZFIN Ensembl
fruit fly
First Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled., Development 1995                
Most Recent Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Cells Tissues Organs 2021  
All View All Papers 54 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 16 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 44 terms 28 terms 0 term
KEGG Pathways K02353 K02353
KOG [R] Dishevelled 3 and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dvl2
Antibodies Dvl2 Ab1 , Dvl2 Ab2 , Dvl2 Ab3 , dvl2 Ab4 Dvl2 Ab1 , Dvl2 Ab2 , Dvl2 Ab3 , dvl2 Ab4 dvl2 Ab4
Morpholinos dvl2 MO1 , dvl2 MO2 , dvl2 MO3 dvl2 MO1 , dvl2 MO2 , dvl2 MO3
ORFs dvl2 ORF1 dvl2.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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