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Summary Expression Gene Literature (91) GO Terms (58) Nucleotides (407) Proteins (55) Interactants (724) Wiki
XB-GENEPAGE-1019625
Gene Symbol:
aurkb

Gene Name:
aurora kinase B

Synonyms:
aik2 , aurora B , aim1 , ark2 , AurB , ipl1 , stk5 , stk12 , airk2 , aurkb-a , aurkb-b ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ens...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1019626 XB-GENE-1019634 XB-GENE-6256242
Gene Symbol aurkb aurkb.L aurkb.S
Chromosome Chr3 chr3L Scaffold20
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549613
398457
444083
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine aurkb aurkb.L aurkb.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tegg085p18      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards AURKB OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Aurkb MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Aurkb Ensembl
zebrafish
ZFIN, AGR aurkb ZFIN Ensembl
chicken
GEISHA AURKB Ensembl
fruit fly
Publications
First Cell-cycle-dependent expression of the STK-1 gene encoding a novel murine putative protein kinase., Gene 1996  
Most Recent The Borealin dimerization domain interacts with Sgo1 to drive Aurora B-mediated spindle assembly., Mol Biol Cell 2020            
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 56 terms 31 terms 28 terms
PANTHER aurkb
KEGG Pathways K11479 K11479 K11479
KOG [D] Serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks aurkb
Antibodies Aurkb Ab1 , Aurkb Ab2 , aurka/b Ab1 Aurkb Ab1 , Aurkb Ab2 , aurka/b Ab1 Aurkb Ab1 , Aurkb Ab2 , aurka/b Ab1
Morpholinos aurkb MO1 aurkb MO1 aurkb MO1
ORFs aurkb ORF1 aurkb.L ORF1 aurkb.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info