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Summary Expression Gene Literature (9) GO Terms (19) Nucleotides (1306) Proteins (44) Interactants (355) Wiki
XB-GENEPAGE-969446
Gene Symbol:
tubb4b

Gene Name:
tubulin beta 4B class IVb

Synonyms:
tubb2 , tubb2c , oocyte tubulin , XLOT ( Add synonyms , Nomenclature history )

Gene Function:
microtubule component

Protein Function :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.



Interactants:
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Diseases: 


OMIM:
LEBER CONGENITAL AMAUROSIS WITH EARLY-ONSET DEAFNESS; LCAEOD

External Links:
 
Xenbase Gene ID XB-GENE-969447 XB-GENE-969453 XB-GENE-17341812
Gene Symbol tubb4b tubb4b.L tubb4b.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779904
380258
379202
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tubb4b tubb4b.L tubb4b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TUBB4B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tubb4b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tubb4b Ensembl
zebrafish
ZFIN, AGR tubb4b ZFIN Ensembl
chicken
GEISHA TUBB4B Ensembl
fruit fly
Publications
First The multiple beta-tubulin genes of Xenopus: isolation and developmental expression of a germ-cell isotype beta-tubulin gene., Differentiation 1992              
Most Recent Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest., Development 2018                            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 6 terms 6 terms
PANTHER tubb4b
KEGG Pathways K07375 K07375 K07375
KOG [Z] Beta tubulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tubb4b
ORFs tubb4b ORF1 , tubb4b ORF2 , tubb4b ORF3 tubb4b.L ORF1 MGC53997 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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