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Summary Expression Gene Literature (4) GO Terms (6) Nucleotides (16) Proteins (13) Interactants (39) Wiki
XB-GENEPAGE-22061503
Gene Symbol:
hyls1

Gene Name:
centriolar and ciliogenesis associated

Synonyms:
hyles1 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Plays an important role in ciliogenesis. Required for apical targeting/anchoring of centrioles at the plasma membrane.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Joubert syndrome [+]

OMIM:
HYDROLETHALUS SYNDROME 1; HLS1

External Links:
 
Xenbase Gene ID XB-GENE-22061504 XB-GENE-22061505 XB-GENE-22061506
Gene Symbol hyls1 hyls1.L hyls1.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 101731869
108701712
108703259
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL NCBI Protein Swiss-Prot
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hyls1 hyls1.L hyls1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards HYLS1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hyls1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hyls1 Ensembl
zebrafish
chicken
GEISHA HYLS1 Ensembl
fruit fly
Publications
First The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation., Genes Dev 2009                  
Most Recent Foxn4 promotes gene expression required for the formation of multiple motile cilia., Development 2016                                    
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 4 terms 5 terms
PANTHER hyls1
KEGG Pathways K16472 K16472 K16472
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hyls1
Antibodies hyls1 Ab1 hyls1 Ab1 hyls1 Ab1
Morpholinos hyls1 MO1 , hyls1 MO2
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

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