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Summary Expression Gene Literature (901) GO Terms (32) Nucleotides (256) Proteins (52) Interactants (2566) Wiki
XB-GENEPAGE-478788
Gene Symbol:
tbxt

Gene Name:
T-box transcription factor T

Synonyms:
Xbra , X-bra , bra , Xbrachyury , brachyury , ntl , t-a , t-b , t ( Add synonyms , Nomenclature history )

Gene Function:
nuclear transcription factor

Protein Function :
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]


InterPro :
T-box sf , p53-like TF DNA-bd , TF T-box CS , TF T-box [+]

Interactants:
Loading ...

Diseases: 


OMIM:
NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD [+]

External Links:
GEO Series :
GSE48663.
1/6
 
Xenbase Gene ID XB-GENE-478789 XB-GENE-6255736 XB-GENE-865212
Gene Symbol tbxt tbxt.L tbxt.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493501
432248
399275
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tbxt tbxt.L tbxt.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas116l23      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TBXT OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR T MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tbxt Ensembl
zebrafish
ZFIN, AGR tbxtb tbxta ZFIN Ensembl
chicken
GEISHA TBXT Ensembl
fruit fly
FLYBASE t Ensembl
worm
Publications
First Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo., Proc Natl Acad Sci U S A 1980  
Most Recent Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021                  
All View All Papers 207 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 20 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 4 terms 10 terms
PANTHER tbxt
KEGG Pathways K12190 [+] K10172 K10172
KOG [K] TBX2 and related T-box transcription factors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tbxt
Mutants Xtr.tbxtemJcsm , Xtr.tbxt,tbxt.2emJcsm
Antibodies Tbxt Ab1 , Tbxt Ab2 Tbxt Ab1 , Tbxt Ab2 Tbxt Ab1 , Tbxt Ab2
Morpholinos (on-target & off-target) tbxt MO4 , tbxt MO2 , tbxt MO3 tbxt MO1 tbxt MO1
ORFs tbxt ORF1 tbxt.L ORF1 tbxt.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info