|
XB-GENEPAGE-478788
Gene Symbol:
tbxt
Gene Name: T-box transcription factor T
Synonyms:
Xbra
,
X-bra
,
bra
,
Xbrachyury
,
brachyury
,
ntl
,
t-a
,
t-b
,
t
( Gene Function: nuclear transcription factor Protein Function
![]()
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]
Interactants:
Loading ...
Diseases: OMIM:
NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD
External Links:
|
|
Xenbase Gene ID | XB-GENE-478789 | XB-GENE-6255736 | XB-GENE-865212 | |||||
Gene Symbol | tbxt | tbxt.L | tbxt.S | Chromosome | Chr5 | chr5L | chr5S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.1
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
Gene model
![]() |
|||||
Entrez Gene |
493501
|
432248
|
399275
|
|||||
mRNA |
RefSeq
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
|||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
|||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
|
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | tbxt | tbxt.L | tbxt.S | |||||
Phenotype | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Smith Morpholino Screen | tgas116l23 | |||||||
Orthology |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
worm |
|
|||||||
Publications | ||||||||
First |
Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo., Proc Natl Acad Sci U S A 1980 |
|||||||
Most Recent |
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021 ![]() |
|||||||
All | View All Papers 207 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 20 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 28 terms | 4 terms | 10 terms | |||||
PANTHER | tbxt | |||||||
KEGG Pathways | K12190 [+] | K10172 | K10172 | |||||
KOG |
[K] TBX2 and related T-box transcription factors
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | tbxt | |||||||
Mutants | Xtr.tbxtemJcsm , Xtr.tbxt,tbxt.2emJcsm | |||||||
Antibodies | Tbxt Ab1 , Tbxt Ab2 | Tbxt Ab1 , Tbxt Ab2 | Tbxt Ab1 , Tbxt Ab2 | |||||
Morpholinos (on-target & off-target) | tbxt MO4 , tbxt MO2 , tbxt MO3 | tbxt MO1 | tbxt MO1 | |||||
ORFs | tbxt ORF1 | tbxt.L ORF1 | tbxt.S ORF1 | |||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



