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Summary Expression Gene Literature (18) GO Terms (25) Nucleotides (89) Proteins (41) Interactants (289) Wiki
XB-GENEPAGE-479666
Gene Symbol:
pou3f4

Gene Name:
POU class 3 homeobox 4

Synonyms:
brn4 , XlPOU2 , XlPOU 2 , XlPOU-2 , POU 2 , pou2 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcriptional activator. Induces neural-specific gene expression to act as a key regulator of neural differentiation.


InterPro :
P-loop NTPase , Myosin TH1 , MYSc Myo1 , Kinesin motor dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
X-linked nonsyndromic deafness [+]

OMIM:
DEAFNESS, X-LINKED 2; DFNX2

External Links:
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Xenbase Gene ID XB-GENE-479667 XB-GENE-865294 XB-GENE-17346234
Gene Symbol pou3f4 pou3f4.L pou3f4.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100036711
397929
444776
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pou3f4 pou3f4.L pou3f4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards POU3F4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pou3f4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pou3f4 Ensembl
zebrafish
chicken
GEISHA POU3F4 Ensembl
fruit fly
worm
Publications
First XLPOU 1 and XLPOU 2, two novel POU domain genes expressed in the dorsoanterior region of Xenopus embryos., Dev Biol 1991                    
Most Recent Pou3f transcription factor expression during embryonic development highlights distinct pou3f3 and pou3f4 localization in the Xenopus laevis kidney., Int J Dev Biol 2018                                                                        
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 24 terms 8 terms 7 terms
PANTHER pou3f4
KEGG Pathways K09365 K09365 K09365
KOG [K] Transcription factor OCT-1, contains POU and HOX domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pou3f4
Mutants Xtr.pou3f4emHorb
ORFs pou3f4 ORF1 pou3f4.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info