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Summary Expression Gene Literature (25) GO Terms (12) Nucleotides (165) Proteins (45) Interactants (376) Wiki
XB-GENEPAGE-480578
Gene Symbol:
spry1

Gene Name:
sprouty RTK signaling antagonist 1

Synonyms:
sprouty , sprouty1 , sprouty-1 , sprouty 1 , Xtsprouty1 , xspry1 , spry1-a , spry1-b ( Add synonyms , Nomenclature history )

Gene Function:
regulation of signal transduction

Protein Function :


InterPro :
TPR-like helical dom sf , TPR-contain dom , TPR repeat , SPRY1 [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480579 XB-GENE-6007713 XB-GENE-6372210
Gene Symbol spry1 spry1.L spry1.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 449470
100192368
100294515
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine spry1 spry1.L spry1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SPRY1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Spry1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Spry1 Ensembl
zebrafish
spry1 Ensembl
chicken
GEISHA SPRY1 Ensembl
fruit fly
Publications
First naked cuticle encodes an inducible antagonist of Wnt signalling., Nature 2000  
Most Recent Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway., Sci Rep 2020                        
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 7 terms 7 terms
PANTHER spry1
KEGG Pathways K04704 K04704 K04704
KOG [T] Signal transduction protein Enabled, contains WH1 domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks spry1
Morpholinos spry1 MO1 , spry1 MO2 spry1 MO1 , spry1 MO2 spry1 MO1 , spry1 MO2
ORFs spry1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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