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Summary Expression Gene Literature (180) GO Terms (27) Nucleotides (57) Proteins (33) Interactants (209) Wiki
XB-GENEPAGE-481755
Gene Symbol:
il1b

Gene Name:
interleukin 1 beta

Synonyms:
IL-1B , interleukin-1-beta , IL-1 ( Add synonyms , Nomenclature history )

Gene Function:
cytokine

Protein Function :
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-ce...[+]


InterPro :
cAMP dep PKI , VHS dom , UIM dom , Znf FYVE PHD [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
stomach cancer

OMIM:
GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC

External Links:
1/4
 
Xenbase Gene ID XB-GENE-481756 XB-GENE-17342546 XB-GENE-865486
Gene Symbol il1b il1b.L il1b.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100487038
108711577
373606
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine il1b il1b.L il1b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards IL1B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Il1b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Il1b Ensembl
zebrafish
ZFIN, AGR il1b ZFIN Ensembl
chicken
GEISHA IL1B Ensembl
fruit fly
worm
Publications
First Nucleotide sequence of human monocyte interleukin 1 precursor cDNA., Proc Natl Acad Sci U S A 1984  
Most Recent The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation., Development 2020                                      
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 27 terms 0 term 9 terms
PANTHER il1b
KEGG Pathways K04519
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks il1b
Antibodies Il1b Ab1 Il1b Ab1
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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