Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (14) GO Terms (5) Nucleotides (79) Proteins (24) Interactants (176) Wiki
Gene Symbol:

Gene Name:
frizzled class receptor 1

Xfrizzled-1 , Fz-1 , Xfz1 , frizzled-1 , frizzled1 , frz1 , frz-1 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane receptor in the wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10969734). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled protei...[+]

Loading ...


External Links:
Xenbase Gene ID XB-GENE-481861 XB-GENE-865493 XB-GENE-17342011
Gene Symbol fzd1 fzd1.L fzd1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100145232
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fzd1 fzd1.L fzd1.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards FZD1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Fzd1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Fzd1 Ensembl
ZFIN, AGR fzd1 ZFIN Ensembl
fruit fly
First Dishevelled: at the crossroads of divergent intracellular signaling pathways., Mech Dev 1999    
Most Recent TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Elife 2020                                                                                            
All View All Papers 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 5 terms 0 term
KEGG Pathways K02432 K02432
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fzd1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info