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Summary Expression Phenotypes Gene Literature (485) GO Terms (9) Nucleotides (57) Proteins (31) Interactants (1528) Wiki
XB-GENEPAGE-483208
Gene Symbol :
nodal

Gene Name :
nodal growth differentiation factor

Synonyms:
Xnr-4 , Xnr4 , nr4 , nodal4 , Nodal homolog 4 [-] ( Add synonyms , Nomenclature history )

Gene Function:
transforming growth factor beta and bone morphogenetic protein related protein

Protein Function :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Plays a role in mesoderm formation and may be required for neural development.


InterPro :
TGF-b propeptide , TGF-beta-rel , Cystine-knot cytokine , TGF-b C [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
situs inversus

OMIM:
HETEROTAXY, VISCERAL, 5, AUTOSOMAL; HTX5

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Phenotype
Smith Morpholino Screen tgas097d22      

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info