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Summary Expression Phenotypes Gene Literature (47) GO Terms (10) Nucleotides (104) Proteins (43) Interactants (479) Wiki
XB-GENEPAGE-485116
Gene Symbol :
lrp5

Gene Name :
LDL receptor related protein 5

Synonyms:
Xlrp5 , hbm , lr3 , ops , evr1 , evr4 , lrp7 , oppg , bmnd1 , opta1 , vbch2 ( Add synonyms , Nomenclature history )

Gene Function:
Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains

Protein Function :
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.


Interactants:
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

OMIM:
OSTEOPOROSIS [+]

External Links:
 
Expression                  Development Stages                                               Embryonic Tissuesd                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info