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Summary Expression Phenotypes Gene Literature (51) GO Terms (10) Nucleotides (108) Proteins (44) Interactants (491) Wiki
XB-GENEPAGE-485116
Gene Symbol :
lrp5
Symbol Status : Curated


Gene Name :
LDL receptor related protein 5
Name Status : Curated


Synonyms:
Xlrp5 , hbm , lr3 , ops , evr1 , evr4 [+] ( Add synonyms , Nomenclature history )

Gene Function:
Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains

Protein Function :
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.



Interactants:
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

OMIM:
OSTEOPOROSIS [+]

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:

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