Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (23) GO Terms (4) Nucleotides (45) Proteins (23) Interactants (536) Wiki
XB-GENEPAGE-486594
Gene Symbol:
wnt2

Gene Name:
Wnt family member 2

Synonyms:
Xwnt2 , Xwnt-2 , wnt-2 , irp , int1l1 ( Add synonyms , Nomenclature history )

Gene Function:
secreted growth factor/developmental regulator

Protein Function :
Ligand for members of the frizzled family of seven transmembrane receptors.


InterPro :
2pore dom K chnl , 2pore dom K chnl TWIK , 2pore dom K chnl TWIK1 , K chnl dom [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-486595 XB-GENE-17333728 XB-GENE-17333729
Gene Symbol wnt2 wnt2.L wnt2.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 100038261
108711137
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine wnt2 wnt2.L wnt2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards WNT2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wnt2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wnt2 Ensembl
zebrafish
ZFIN, AGR wnt2 ZFIN Ensembl
chicken
GEISHA WNT2 Ensembl
fruit fly
FLYBASE Wnt2 Ensembl
Publications
First Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family., Oncogene 1992  
Most Recent Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains., Nat Commun 2020              
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 4 terms 0 term
PANTHER wnt2
KEGG Pathways K00182 K00182
KOG [T] Wnt family of developmental regulators
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks wnt2
Morpholinos wnt2 MO1 wnt2 MO1
Clones Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info