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Summary Expression Gene Literature (29) GO Terms (36) Nucleotides (154) Proteins (43) Interactants (891) Wiki
Gene Symbol:

Gene Name:
hes related family bHLH transcription factor with YRPW motif 1

hrt1 , XHRT1 , chf2 , hrt-1 , hesr1 , herp2 , oaf1 , bc8 ( Add synonyms , Nomenclature history )

Gene Function:
helix-loop-helix transcription factor/transcriptional repressor

Protein Function :
Downstream effector of Notch signaling. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Acts as a suppressor of neurogenesis by antagonizing proneural...[+]

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External Links:
Xenbase Gene ID XB-GENE-486694 XB-GENE-17344247 XB-GENE-865637
Gene Symbol hey1 hey1.L hey1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493293
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hey1 hey1.L hey1.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards HEY1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Hey1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Hey1 Ensembl
ZFIN, AGR hey1 ZFIN Ensembl
fruit fly
First Microinjection of purified ornithine decarboxylase into Xenopus oocytes selectively stimulates ribosomal RNA synthesis., Proc Natl Acad Sci U S A 1983  
Most Recent Recovery of the Xenopus laevis heart from ROS-induced stress utilizes conserved pathways of cardiac regeneration., Dev Growth Differ 2019                
All View All Papers 8 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 33 terms 6 terms 18 terms
KEGG Pathways K00658 [+] K09091 K09091
KOG [K] Transcriptional repressors of the hairy/E(spl) family (contains HLH)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hey1
Morpholinos hey1 MO1 , hey1 MO2 hey1 MO1 , hey1 MO2 hey1 MO1 , hey1 MO2
ORFs hey1 ORF1 hey1.S ORF1
Clones EXRC Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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