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Summary Expression Gene Literature (6) GO Terms (15) Nucleotides (40) Proteins (18) Interactants (110) Wiki
XB-GENEPAGE-5961525
Gene Symbol:
deup1

Gene Name:
deuterosome assembly protein 1

Synonyms:
ccdc67 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differen...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5961526 XB-GENE-17340393 XB-GENE-17340394
Gene Symbol deup1 deup1.L deup1.S
Chromosome Chr2 chr2L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100380182
108708754
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine deup1 deup1.L deup1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards DEUP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Deup1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Deup1 Ensembl
zebrafish
chicken
GEISHA DEUP1 Ensembl
fruit fly
Publications
First The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis., Nat Cell Biol 2013  
Most Recent A role for Cep70 in centriole amplification in multiciliated cells., Dev Biol 2021  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 4 terms 0 term
PANTHER deup1
KEGG Pathways K00799
KOG [S] Uncharacterized conserved coiled-coil protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks deup1
Clones Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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