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Summary Expression Gene Literature (56) GO Terms (17) Nucleotides (119) Proteins (45) Interactants (755) Wiki
Gene Symbol:

Gene Name:
gastrulation brain homeobox 2, gene 2

XGBX-2 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
May act as a transcription factor for cell pluripotency and differentiation in the embryo.

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External Links:
Xenbase Gene ID XB-GENE-852624 XB-GENE-866652 XB-GENE-17339133
Gene Symbol gbx2.2 gbx2.2.L gbx2.2.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496963
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gbx2.2 gbx2.2.L gbx2.2.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards GBX2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Gbx2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Gbx2 Ensembl
ZFIN, AGR gbx2 ZFIN Ensembl
fruit fly
First The Xenopus laevis homeobox gene Xgbx-2 is an early marker of anteroposterior patterning in the ectoderm., Mech Dev 1996            
Most Recent Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos., Anim Cells Syst (Seoul) 2020              
All View All Papers 17 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 5 terms 5 terms
PANTHER gbx2.2
KEGG Pathways K09321 K09321 K09321
KOG [R] Transcription factor zerknullt and related HOX domain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gbx2.2
Morpholinos gbx2.1 MO1 gbx2.1 MO1 , gbx2.2 MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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