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Summary Expression Gene Literature (272) GO Terms (17) Nucleotides (59) Proteins (35) Interactants (1387) Wiki
XB-GENEPAGE-853107
Gene Symbol:
en2

Gene Name:
engrailed homeobox 2

Synonyms:
engrailed homolog 2 , En-2 , engrailed-2 , engrailed 2 , eng2 , xen2 , maben , en2-a , en2-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :


InterPro :
BPL C , Biotin-prot ligase N , Biotin CoA COase ligase , BPL LPL catalytic [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
autistic disorder

OMIM:
AUTISM, SUSCEPTIBILITY TO, 10; AUTS10

External Links:
1/3
 
Xenbase Gene ID XB-GENE-853108 XB-GENE-866462 XB-GENE-6254047
Gene Symbol en2 en2.L en2.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100498251
378588
399321
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine en2 en2.L en2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards EN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR En2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR En2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR en2a en2b ZFIN Ensembl
chicken
GEISHA EN2 Ensembl
fruit fly
Publications
First Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos., Development 1989                    
Most Recent Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Genesis 2021            
All View All Papers 79 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 6 terms 6 terms
PANTHER en2
KEGG Pathways K09319 K09319 K09319
KOG [R] Transcription factor Engrailed, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks en2
Antibodies En2 Ab1 , En2 Ab3 En2 Ab1 , En2 Ab3 En2 Ab1 , En2 Ab3
Morpholinos en2 MO1 en2 MO1 en2 MO1
Clones Horizon Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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