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Summary Expression Gene Literature (169) GO Terms (43) Nucleotides (114) Proteins (44) Interactants (886) Wiki
Gene Symbol:

Gene Name:
glycogen synthase kinase 3 beta

gsk3 , gsk-3 , Xgsk-3 , gsk3beta , gsk3-beta ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase, wnt signal transduction

Protein Function :
Plays a role in the organization of the formation of the main body axis of developing embryo. Acts as an inhibitor of differentiation of primary neurons. Inhibits the ability of ectopically expressed N...[+]

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External Links:
Xenbase Gene ID XB-GENE-487098 XB-GENE-865674 XB-GENE-17333303
Gene Symbol gsk3b gsk3b.L gsk3b.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100489648
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gsk3b gsk3b.L gsk3b.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards GSK3B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Gsk3b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Gsk3b Ensembl
ZFIN, AGR ZFIN, AGR gsk3ba gsk3bb ZFIN Ensembl
fruit fly
First Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3., Development 1995                
Most Recent Establishing embryonic territories in the context of Wnt signaling., Int J Dev Biol 2021        
All View All Papers 17 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 39 terms 12 terms 0 term
KEGG Pathways K03083
KOG [G] Glycogen synthase kinase-3
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gsk3b
Antibodies Gsk3a/b Ab1 Gsk3a/b Ab1
Morpholinos gsk3b MO1
ORFs gsk3b.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info