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Summary Expression Gene Literature (9) GO Terms (16) Nucleotides (169) Proteins (43) Interactants (277) Wiki
XB-GENEPAGE-876464
Gene Symbol:
hes7.1

Gene Name:
hairy and enhancer of split 7, gene 1

Synonyms:
HES-related 1 , XHR1 ( Add synonyms , Nomenclature history )

Gene Function:
helix-loop-helix transcription factor/transcriptional repressor

Protein Function :
Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. Demarcates the prospective midbrain-hindbrain boundary (MHB) region in the neuroectoderm in early gas...[+]


InterPro :
HLH DNA-bd sf , Orange dom , bHLH dom , Znf C2H2 sf [+]

Interactants:
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Diseases: 


Disease Ontology:
spondylocostal dysostosis

OMIM:
SPONDYLOCOSTAL DYSOSTOSIS 4, AUTOSOMAL RECESSIVE; SCDO4

External Links:
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Xenbase Gene ID XB-GENE-876465 XB-GENE-876475 XB-GENE-17334743
Gene Symbol hes7.1 hes7.1.L hes7.1.S
Chromosome Chr3 chr3L Scaffold20
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 733997
398267
108703526
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hes7.1 hes7.1.L hes7.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards HES7 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hes7 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hes7 Ensembl
zebrafish
chicken
GEISHA HES7 Ensembl
fruit fly
Publications
First Early patterning of the prospective midbrain-hindbrain boundary by the HES-related gene XHR1 in Xenopus embryos., Mech Dev 2001            
Most Recent Six1 and Eya1 both promote and arrest neuronal differentiation by activating multiple Notch pathway genes., Dev Biol 2017                              
All View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 7 terms 0 term
PANTHER hes7.1
KEGG Pathways
KOG [K] Transcriptional repressors of the hairy/E(spl) family (contains HLH)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hes7.1
Morpholinos hes7.1 MO1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info