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Summary Expression Gene Literature (18) GO Terms (20) Nucleotides (285) Proteins (62) Interactants (748) Wiki
Gene Symbol:

Gene Name:
transducin like enhancer of split 2

esg2 , grg2 , Xesg1 , tle3 , esg3 , grg3 , esg , tle3a , esg1 , xgrg3 ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional regulator

Protein Function :
Nuclear effector molecule.

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External Links:
Xenbase Gene ID XB-GENE-876620 XB-GENE-876631 XB-GENE-17342894
Gene Symbol tle2 tle2.L tle2.S
Chromosome Chr1 chr1L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 548559
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tle2 tle2.L tle2.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards TLE2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Tle2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Tle2 Ensembl
ZFIN, AGR tle2a tle2b ZFIN Ensembl
fruit fly
First The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes., Mech Dev 1992  
Most Recent High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Dev Biol 2017                    
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 2 terms 0 term
KEGG Pathways
KOG [B] Transducin-like enhancer of split protein (contains WD40 repeats)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tle2
Antibodies Tle1 Ab1 Tle1 Ab1 Tle1 Ab1
Morpholinos tle2 MO1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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