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Summary Expression Gene Literature (42) GO Terms (10) Nucleotides (85) Proteins (32) Interactants (463) Wiki
XB-GENEPAGE-920721
Gene Symbol:
lmna

Gene Name:
lamin A/C

Synonyms:
Lamin-A , lamin a ( Add synonyms , Nomenclature history )

Gene Function:
nucleoskeletal protein

Protein Function :
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also inter...[+]


InterPro :
IF conserved , IF rod dom , IF rod dom coil1B , Lamin tail dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
familial partial lipodystrophy [+]

OMIM:
CARDIOMYOPATHY, DILATED, 1A; CMD1A [+]

External Links:
 
Xenbase Gene ID XB-GENE-920722 XB-GENE-920728 XB-GENE-17342018
Gene Symbol lmna lmna.L lmna.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 733973
373673
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lmna lmna.L lmna.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LMNA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lmna MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lmna Ensembl
zebrafish
ZFIN, AGR lmna ZFIN Ensembl
chicken
GEISHA LMNAL Ensembl
fruit fly
worm
Publications
First Differential expression of nuclear lamin proteins during chicken development., J Cell Biol 1987  
Most Recent Extreme nuclear branching in healthy epidermal cells of the Xenopus tail fin., J Cell Sci 2018  
All View All Papers 2 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 2 terms 0 term
PANTHER lmna
KEGG Pathways K12641 K12641
KOG [DY] Nuclear envelope protein lamin, intermediate filament superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lmna
Mutants Xtr.lmnaemHorb
Antibodies Lmna Ab1 , Lmna Ab2 , Lmnb2/3 Ab5 Lmna Ab1 , Lmna Ab2 , Lmnb2/3 Ab5 Lmna Ab2 , Lmnb2/3 Ab5
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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