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Summary Expression Phenotypes Gene Literature (1) GO Terms (8) Nucleotides (189) Proteins (39) Interactants (67) Wiki
XB-GENEPAGE-950143
Gene Symbol :
erlin2

Gene Name :
ER lipid raft associated 2

Synonyms:
spfh2 , erlin2-a , erlin2-b ( Add synonyms , Nomenclature history )

Gene Function:
Prohibitin-related membrane protease subunits

Protein Function :
Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Promotes sterol-accelerated ERAD of HMGCR. Involved in regulation of cellular cholest...[+]


Interactants:
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Diseases: 


Disease Ontology:
hereditary spastic paraplegia 18

OMIM:
SPASTIC PARAPLEGIA 18, AUTOSOMAL RECESSIVE; SPG18

External Links:
 
Expression                  Development Stages                                               Embryonic Tissuesd                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info