Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (16) GO Terms (8) Nucleotides (132) Proteins (47) Interactants (224) Wiki
XB-GENEPAGE-950816
Gene Symbol:
sag

Gene Name:
S-antigen; retina and pineal gland (arrestin)

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Arrestin

Protein Function :
Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO. May play a role in preventing light-dependent dege...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
retinitis pigmentosa 47 [+]

OMIM:
OGUCHI DISEASE 1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-950817 XB-GENE-17335209 XB-GENE-950824
Gene Symbol sag sag.L sag.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394670
398109
447588
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sag sag.L sag.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SAG OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sag MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sag Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR saga sagb ZFIN Ensembl
chicken
GEISHA SAG Ensembl
fruit fly
FLYBASE sag Ensembl
Publications
First Immediate upstream sequence of arrestin directs rod-specific expression in Xenopus., J Biol Chem 1999                
Most Recent STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells., Nat Commun 2020                  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 4 terms 2 terms
PANTHER sag
KEGG Pathways K19627 K19627 K19627
KOG [T] Arrestin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sag
ORFs sag ORF1 sag.L ORF1 sag.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info