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Summary Expression Gene Literature (69) GO Terms (38) Nucleotides (256) Proteins (44) Interactants (698) Wiki
XB-GENEPAGE-973459
Gene Symbol:
vangl2

Gene Name:
VANGL planar cell polarity protein 2

Synonyms:
stb1 , strabismus , Xstrabismus , stbm1 , stbm , Van Gogh , vang-like 2 , vangl2-a , vangl2-b , ltap , lpp1 ( Add synonyms , Nomenclature history )

Gene Function:
Non-canonical wnt pathway signaling protein

Protein Function :
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane. Acts in a PCP complex to regulate the polarized assembly...[+]


InterPro :
DOP1 , Dopey N , VANGL , Histone H5 [+]

Interactants:
Loading ...

Diseases: 


OMIM:
NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD

External Links:
1/2
 
Xenbase Gene ID XB-GENE-973460 XB-GENE-6251797 XB-GENE-973465
Gene Symbol vangl2 vangl2.L vangl2.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 613073
398271
399177
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine vangl2 vangl2.L vangl2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards VANGL2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Vangl2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Vangl2 Ensembl
zebrafish
ZFIN, AGR vangl2 ZFIN Ensembl
chicken
GEISHA VANGL2 Ensembl
fruit fly
Publications
First Eye-specific segregation of optic afferents in mammals, fish, and frogs: the role of activity., Cell Mol Neurobiol 1985  
Most Recent Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Development 2021  
All View All Papers 8 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 37 terms 9 terms 8 terms
PANTHER vangl2
KEGG Pathways K04510 K04510 K04510
KOG [T] Signaling protein van gogh/strabismus
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks vangl2
Antibodies Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 , Vangl2 Ab4 , Vangl2 Ab5 Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 , Vangl2 Ab4 , Vangl2 Ab5 Vangl2 Ab1 , Vangl2 Ab2 , Vangl2 Ab3 , Vangl2 Ab4 , Vangl2 Ab5
Morpholinos vangl2 MO3 , vangl2 MO1 , vangl2 MO2 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 , vangl2 MO7 vangl2 MO3 , vangl2 MO1 , vangl2 MO2 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 , vangl2 MO7 vangl2 MO3 , vangl2 MO1 , vangl2 MO2 , vangl2 MO4 , vangl2 MO5 , vangl2 MO6 , vangl2 MO7
ORFs vangl2.L ORF1 vangl2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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