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Summary Expression Gene Literature (124) GO Terms (19) Nucleotides (41) Proteins (27) Interactants (120) Wiki
XB-GENEPAGE-991583
Gene Symbol:
kcna2

Gene Name:
potassium channel, voltage gated shaker related subfamily A, member 2

Synonyms:
kv1.2 , k(v)1.2 ( Add synonyms , Nomenclature history )

Gene Function:
Voltage-gated shaker-like K+ channel KCNA

Protein Function :
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and central nervous system. Prevents aberrant action potential firing and ...[+]



Interactants:
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Diseases: 


Disease Ontology:
developmental and epileptic encephalopathy 32

OMIM:
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 32; DEE32

External Links:
 
Xenbase Gene ID XB-GENE-991578 XB-GENE-991585 XB-GENE-17341622
Gene Symbol kcna2 kcna2.L kcna2.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100496794
373840
108709388
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kcna2 kcna2.L kcna2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards KCNA2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kcna2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kcna2 Ensembl
zebrafish
LOC100537815 Ensembl
chicken
GEISHA KCNA2 Ensembl
fruit fly
Publications
First Effects of the level of mRNA expression on biophysical properties, sensitivity to neurotoxins, and regulation of the brain delayed-rectifier K+ channels Kv1.2., Biochemistry 1992  
Most Recent Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine., J Pharmacol Exp Ther 2020  
All View All Papers 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 9 terms 4 terms
PANTHER kcna2
KEGG Pathways K00069 [+] K04875 K04875
KOG [P] Voltage-gated shaker-like K+ channel KCNA
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kcna2
Antibodies Kcna3 Ab1 Kcna2 Ab1
Clones Horizon EXRC Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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