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Summary Expression Gene Literature (10) GO Terms (13) Nucleotides (230) Proteins (36) Interactants (366) Wiki
XB-GENEPAGE-997461
Gene Symbol:
suz12

Gene Name:
SUZ12, polycomb repressive complex 2 subunit

Synonyms:
chet9 , jjaz1 , Xsuz12 ( Add synonyms , Nomenclature history )

Gene Function:
Zn-finger protein joined to JAZF1 (predicted suppressor)

Protein Function :
Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected targe...[+]



Interactants:
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Diseases: 


Disease Ontology:
Weaver syndrome

External Links:
1/4
 
Xenbase Gene ID XB-GENE-997462 XB-GENE-17336234 XB-GENE-5970792
Gene Symbol suz12 suz12.L suz12.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779745
108701224
100174799
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine suz12 suz12.L suz12.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SUZ12 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Suz12 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Suz12 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR suz12b suz12a ZFIN Ensembl
chicken
GEISHA SUZ12 Ensembl
fruit fly
Publications
First Characterization of the expression pattern of the PRC2 core subunit Suz12 during embryonic development of Xenopus laevis., Dev Dyn 2009                      
Most Recent Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction., Nat Commun 2021        
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 1 terms 0 term
PANTHER suz12
KEGG Pathways K11463 K11463
KOG [R] Zn-finger protein joined to JAZF1 (predicted suppressor)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks suz12
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info