Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (41) GO Terms (6) Nucleotides (223) Proteins (47) Interactants (797) Wiki
XB-GENEPAGE-486940
Gene Symbol :
prickle1

Gene Name :
prickle planar cell polarity protein 1

Synonyms:
prickle , XPk , Prickle-b , XPk-1 , prickle1-b , prickle1-a [+] ( Add synonyms , Nomenclature history )

Gene Function:
nuclear receptor, may be a negative regulator of the Wnt/beta-catenin signaling pathway [Entrez]

Protein Function :
Acts in a planar cell polarity (PCP) complex; polarization along the apical/basal axis of epithelial cells. Regulates the polarized assembly of fibronectrin on the surface of the mesoderm during gastru...[+]


InterPro :
Glyco trans 1 , GPCR 2 extracellular dom , GCPR 2 calcitonin rcpt fam , GPCR 2 extracell dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Unverricht-Lundborg syndrome [+]

OMIM:
EPILEPSY, PROGRESSIVE MYOCLONIC, 1B; EPM1B

External Links:
1/7
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info