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Summary Expression Gene Literature (45) GO Terms (21) Nucleotides (1330) Proteins (57) Interactants (817) Wiki
XB-GENEPAGE-495260
Gene Symbol:
id3

Gene Name:
inhibitor of DNA binding 3, HLH protein

Synonyms:
xid3 , heir-1 , xidia , xIdx , id3-a , id3-b ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional regulator

Protein Function :
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA bindin...[+]


InterPro :
DNA-bd prot-inh , HLH DNA-bd sf , bHLH dom , Ig-like dom [+]

Interactants:
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Diseases: 


External Links:
1/5
 
Xenbase Gene ID XB-GENE-495261 XB-GENE-6256366 XB-GENE-866418
Gene Symbol id3 id3.L id3.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549025
379222
379447
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine id3 id3.L id3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ID3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Id3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Id3 Ensembl
zebrafish
ZFIN, AGR id3 ZFIN Ensembl
chicken
GEISHA ID3 Ensembl
fruit fly
worm
Publications
First XIdx, a dominant negative regulator of bHLH function in early Xenopus embryos., Mech Dev 1995            
Most Recent Environmental Oxygen Exposure Allows for the Evolution of Interdigital Cell Death in Limb Patterning., Dev Cell 2019              
All View All Papers 8 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 12 terms 12 terms
PANTHER id3
KEGG Pathways K17694 K17694 K17694
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks id3
Morpholinos (on-target & off-target) id3 MO2 , id3 MO4 , id3 MO5 id3 MO1 , id3 MO2 , id3 MO5 id3 MO1 , id3 MO2 , id3 MO5
ORFs id3.L ORF1 id3.S ORF1
Clones EXRC Horizon Source BioScience EXRC Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info