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Summary Expression Gene Literature (22) GO Terms (36) Nucleotides (221) Proteins (56) Interactants (250) Wiki
XB-GENEPAGE-482710
Gene Symbol:
mdm2

Gene Name:
MDM2 proto-oncogene

Synonyms:
Xdm2 , xdm-2 , double minute-2 ( Add synonyms , Nomenclature history )

Gene Function:
E3 ubiquitin ligase

Protein Function :



Interactants:
Loading ...

Diseases: 


OMIM:
ACCELERATED TUMOR FORMATION, SUSCEPTIBILITY TO; ACTFS

External Links:
 
Xenbase Gene ID XB-GENE-482711 XB-GENE-17332976 XB-GENE-6255114
Gene Symbol mdm2 mdm2.L mdm2.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394853
108711092
108713153
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine mdm2 mdm2.L mdm2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards MDM2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mdm2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mdm2 Ensembl
zebrafish
ZFIN, AGR mdm2 ZFIN Ensembl
chicken
GEISHA MDM2 Ensembl
fruit fly
Publications
First Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis., Oncogene 1997  
Most Recent Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma., Mol Ther Nucleic Acids 2020              
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 36 terms 13 terms 11 terms
PANTHER mdm2
KEGG Pathways K06643 K06643 K06643
KOG [O] Predicted E3 ubiquitin ligase (alt_id KOG:4172)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks mdm2
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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