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Summary Expression Gene Literature (385) GO Terms (23) Nucleotides (85) Proteins (33) Interactants (910) Wiki
XB-GENEPAGE-488110
Gene Symbol:
tgfb1

Gene Name:
transforming growth factor beta 1

Synonyms:
tgfb5 , TGF-beta5 , ced , lap , dpd1 , tgfb , tgfbeta , tgf-beta , tgf-beta 5 , tgf beta , transforming growth factor-B5 , transforming gorwth factor-Beta5 ( Add synonyms , Nomenclature history )

Gene Function:
growth factor

Protein Function :
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active sub...[+]


InterPro :
RIB43A , VWF type-D , MUC2 , Alkaline phosphatase [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
cystic fibrosis [+]

OMIM:
CAMURATI-ENGELMANN DISEASE; CAEND [+]

External Links:
1/7
 
Xenbase Gene ID XB-GENE-488111 XB-GENE-865765 XB-GENE-17343754
Gene Symbol tgfb1 tgfb1.L tgfb1.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100498430
397778
108700276
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tgfb1 tgfb1.L tgfb1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TGFB1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tgfb1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tgfb1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tgfb1a tgfb1b ZFIN Ensembl
chicken
GEISHA TGFB1 Ensembl
fruit fly
worm
Publications
First Time courses of late after-potentials following tetanus or single shock in skeletal muscle fibers., Pflugers Arch 1982  
Most Recent Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos., Anim Cells Syst (Seoul) 2020              
All View All Papers 29 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 22 terms 6 terms 5 terms
PANTHER tgfb1
KEGG Pathways K13375 K13375
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tgfb1
Antibodies Tgfb1 Ab1 , Tgfb1 Ab2 Tgfb1 Ab1 , Tgfb1 Ab2
Morpholinos (on-target & off-target) tgfb1 MO1 tgfb1 MO1 tgfb1 MO1
ORFs tgfb1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info