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XB-GENEPAGE-494199
Gene Symbol:
grin1
Gene Name: glutamate ionotropic receptor NMDA type subunit 1
Synonyms:
NR1
,
nmda1
,
nmdar1
( Gene Function: glutamate receptor channel component Protein Function
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Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requi...[+]
Interactants:
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Diseases: Disease Ontology:
autosomal dominant non-syndromic intellectual disability
OMIM:
NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT HYPERKINETIC MOVEMENTS AND SEIZURES,
External Links:
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Xenbase Gene ID | XB-GENE-494200 | XB-GENE-866327 | XB-GENE-17335935 | |||||
Gene Symbol | grin1 | grin1.L | grin1.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Entrez Gene |
780048
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397953
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mRNA |
RefSeq
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | grin1 | grin1.L | grin1.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs., Nature 1992 |
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Most Recent |
Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology., Nat Commun 2020 ![]() |
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All | View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 28 terms | 11 terms | 0 term | |||||
PANTHER | grin1 | |||||||
KEGG Pathways | K05208 | K05208 | ||||||
KOG |
[PET] NMDA selective glutamate-gated ion channel receptor subunit GRIN1
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | grin1 | |||||||
Antibodies | Grin1 Ab1 , Grin1 Ab2 | Grin1 Ab1 , Grin1 Ab2 | Grin1 Ab1 , Grin1 Ab2 | |||||
Morpholinos (on-target & off-target) | grin1 MO1 , grin1 MO2 | grin1 MO1 , grin1 MO2 | ||||||
ORFs | grin1 ORF1 | |||||||
Clones | Horizon | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



